H13 Antikörper (AA 336-377) (FITC)

Produktnummer ABIN7159824

Der Kaninchen Polyklonal Anti-H13-Antikörper wurde für validiert. Er ist geeignet, H13 in Proben von Human zu detektieren.

Kurzübersicht für H13 Antikörper (AA 336-377) (FITC) (ABIN7159824)

Target: H13 (Histocompatibility 13 (H13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H13 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-H13 Antikörper (FITC)

Bindungsspezifität: AA 336-377

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu H13

Target: H13 (Histocompatibility 13 (H13))

Andere Bezeichnung: HM13

Hintergrund:

Background: Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed:11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed:12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed:12077416, PubMed:11714810, PubMed:14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed:25239945). May play a role in graft rejection (By similarity).

Aliases: dJ324O17.1 antibody, H13 antibody, hIMP1 antibody, Histocompatibility (minor) 13 antibody, HM13 antibody, HM13_HUMAN antibody, IMP-1 antibody, IMP1 antibody, IMPAS antibody, IMPAS-1 antibody, Intramembrane protease 1 antibody, Intramembrane protease antibody, Minor histocompatibility antigen 13 antibody, Minor histocompatibility antigen H13 antibody, MSTP086 antibody, OTTHUMP00000030527 antibody, OTTHUMP00000030528 antibody, OTTHUMP00000030530 antibody, OTTHUMP00000214528 antibody, Presenilin-like protein 3 antibody, PSENL3 antibody, PSL3 antibody, Signal peptide peptidase antibody, Signal peptide peptidase beta antibody, SPP antibody

UniProt: Q8TCT9