ERK2 Antikörper (AA 133-316)

Produktnummer ABIN7159976

Produktdetails anti-ERK2 Antikörper

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Bindungsspezifität: AA 133-316

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mitogen-activated protein kinase 10 protein (133-316AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Andere Bezeichnung: MAPK1 (MAPK1 Produkte)

Synonyme: ERK-1 antikoerper, ERK1 antikoerper, ERT2 antikoerper, HS44KDAP antikoerper, HUMKER1A antikoerper, P44ERK1 antikoerper, P44MAPK antikoerper, PRKM3 antikoerper, p44-ERK1 antikoerper, p44-MAPK antikoerper, Erk-1 antikoerper, Erk1 antikoerper, Ert2 antikoerper, Esrk1 antikoerper, Mnk1 antikoerper, Mtap2k antikoerper, Prkm3 antikoerper, p44 antikoerper, p44erk1 antikoerper, p44mapk antikoerper, ERK antikoerper, ERK2 antikoerper, ERT1 antikoerper, MAPK2 antikoerper, P42MAPK antikoerper, PRKM1 antikoerper, PRKM2 antikoerper, p38 antikoerper, p40 antikoerper, p41 antikoerper, p41mapk antikoerper, 9030612K14Rik antikoerper, AA407128 antikoerper, AU018647 antikoerper, C78273 antikoerper, Erk2 antikoerper, Prkm1 antikoerper, p42mapk antikoerper, zERK2 antikoerper, MAPK1 antikoerper, Xp42 antikoerper, erk antikoerper, erk2 antikoerper, ert1 antikoerper, mapk antikoerper, mapk1b antikoerper, mapk2 antikoerper, mpk1 antikoerper, prkm1 antikoerper, prkm2 antikoerper, mapk1 antikoerper, mapk1a antikoerper, xp42 antikoerper, ATMPK1 antikoerper, F14N23.9 antikoerper, F14N23_9 antikoerper, MITOGEN-ACTIVATED PROTEIN KINASE antikoerper, mitogen-activated protein kinase 1 antikoerper, MNK1 antikoerper, ATMPK2 antikoerper, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antikoerper, T30E16.13 antikoerper, T30E16_13 antikoerper, mitogen-activated protein kinase homolog 2 antikoerper, mitogen-activated protein kinase 3 antikoerper, mitogen-activated protein kinase 1 antikoerper, mitogen activated protein kinase 1 antikoerper, mitogen-activated protein kinase 1 L homeolog antikoerper, mitogen-activated protein kinase 1 S homeolog antikoerper, mitogen activated protein kinase 3 antikoerper, mitogen-activated protein kinase homolog 2 antikoerper, MAPK3 antikoerper, Mapk3 antikoerper, MAPK1 antikoerper, Mapk1 antikoerper, mapk1 antikoerper, mapk1.L antikoerper, mapk1.S antikoerper, PfMAP1 antikoerper, MPK1 antikoerper, PVX_084965 antikoerper, LOC9328617 antikoerper, Tsp_01601 antikoerper, MPK2 antikoerper

Hintergrund:

Background: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).

Aliases: c Jun kinase 3 antibody, c-Jun N-terminal kinase 3 antibody, cJun N terminal kinase 3 antibody, FLJ12099 antibody, FLJ33785 antibody, JNK3 alpha protein kinase antibody, JNK3 antibody, JNK3A antibody, MAP kinase 10 antibody, MAP kinase antibody, MAP kinase p49 3F12 antibody, MAPK 10 antibody, Mapk10 antibody, MGC50974 antibody, mitogen activated protein kinase 10 antibody, Mitogen-activated protein kinase 10 antibody, MK10_HUMAN antibody, p493F12 antibody, p54bSAPK antibody, PRKM10 antibody, protein kinase mitogen activated 10 antibody, SAPK1b antibody, Stress activated protein kinase 1b antibody, stress activated protein kinase beta antibody, Stress activated protein kinase JNK3 antibody, Stress-activated protein kinase JNK3 antibody

UniProt: P53779

Pathways: MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteine