SMAD2 Antikörper (AA 2-467)
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- Target Alle SMAD2 Antikörper anzeigen
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
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Bindungsspezifität
- AA 2-467
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMAD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Mothers against decapentaplegic homolog 2 protein (2-467AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SMAD2 Primärantikörper
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anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3G9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer423), (pSer425), (pSer465), (pSer467) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (C-Term) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibodySMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4D10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pThr183), (pThr221) antibodySMAD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibodySMAD2 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2D7 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 27-172) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IP Wirt: Maus Monoclonal 48-MAD2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 94-112), (N-Term) antibodySMAD2 Reaktivität: Human, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:1000, IF:1:50-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Andere Bezeichnung
- SMAD2 (SMAD2 Produkte)
- Hintergrund
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Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Aliases: Drosophila, homolog of, MADR2 antibody, hMAD-2 antibody, HsMAD2 antibody, JV18 antibody, JV18-1 antibody, JV181 antibody, MAD antibody, MAD homolog 2 antibody, MAD Related Protein 2 antibody, Mad-related protein 2 antibody, MADH2 antibody, MADR2 antibody, MGC22139 antibody, MGC34440 antibody, Mother against DPP homolog 2 antibody, Mothers against decapentaplegic homolog 2 antibody, Mothers against decapentaplegic, Drosophila, homolog of, 2 antibody, Mothers against DPP homolog 2 antibody, OTTHUMP00000163489 antibody, Sma and Mad related protein 2 antibody, Sma- and Mad-related protein 2 MAD antibody, SMAD 2 antibody, SMAD family member 2 antibody, SMAD, mothers against DPP homolog 2 antibody, SMAD2 antibody, SMAD2_HUMAN antibody
- UniProt
- Q15796
- Pathways
- Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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