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SMAD7 Antikörper (AA 36-247)

SMAD7 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7160246
  • Target Alle SMAD7 Antikörper anzeigen
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Bindungsspezifität
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-247
    Reaktivität
    • 45
    • 28
    • 26
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 38
    • 7
    Kaninchen
    Klonalität
    • 39
    • 6
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD7 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 15
    • 14
    • 14
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Mothers against decapentaplegic homolog 7 protein (36-247AA)
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Andere Bezeichnung
    SMAD7 (SMAD7 Produkte)
    Synonyme
    CRCS3 antikoerper, MADH7 antikoerper, MADH8 antikoerper, Smad7a antikoerper, Madh7 antikoerper, Smad10 antikoerper, madh7 antikoerper, xsmad7 antikoerper, wu:fj60c10 antikoerper, SMAD family member 7 antikoerper, SMAD family member 7 L homeolog antikoerper, SMAD7 antikoerper, Smad7 antikoerper, smad7.L antikoerper, smad7 antikoerper
    Hintergrund

    Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    Aliases: CRCS3 antibody, FLJ16482 antibody, hSMAD 7 antibody, hSMAD7 antibody, MAD (mothers against decapentaplegic Drosophila) homolog 7 antibody, MAD antibody, Mad homolog 7 antibody, MAD homolog 8 antibody, MAD mothers against decapentaplegic homolog 7 antibody, MADH 7 antibody, MADH 8 antibody, MADH6 antibody, MADH7 antibody, MADH8 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 6 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 7 antibody, Mothers against decapentaplegic homolog 7 antibody, Mothers against decapentaplegic homolog 8 antibody, Mothers against DPP homolog 7 antibody, Mothers against DPP homolog 8 antibody, SMA- AND MAD-RELATED PROTEIN 7 antibody, SMAD 7 antibody, SMAD antibody, SMAD family member 7 antibody, SMAD, mothers against DPP homolog 7 (Drosophila) antibody, SMAD, mothers against DPP homolog 7 antibody, SMAD6 antibody, Smad7 antibody, SMAD7_HUMAN antibody

    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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