MBNL3 Antikörper (AA 116-211) (Biotin)

Produktnummer ABIN7160362

Produktdetails anti-MBNL3 Antikörper (Biotin)

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Bindungsspezifität: AA 116-211

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Muscleblind-like protein 3 protein (116-211AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MBNL3

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Andere Bezeichnung: MBNL3 (MBNL3 Produkte)

Synonyme: A530038J18Rik antikoerper, AI661274 antikoerper, CHCR antikoerper, E430034C16Rik antikoerper, MBLX antikoerper, MBLX39 antikoerper, MBXL antikoerper, mbxl antikoerper, RGD1565834 antikoerper, muscleblind like splicing regulator 3 antikoerper, muscleblind like splicing factor 3 antikoerper, Muscleblind-like protein 3-like antikoerper, muscleblind-like splicing regulator 3 antikoerper, MBNL3 antikoerper, Mbnl3 antikoerper, mbnl3 antikoerper

Hintergrund:

Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Aliases: A530038J18Rik antibody, AI661274 antibody, CHCR antibody, Cys3His CCG1 required protein antibody, Cys3His CCG1-required protein antibody, E430034C16Rik antibody, MBLX antibody, MBLX39 antibody, MBNL 3 antibody, Mbnl3 antibody, MBNL3_HUMAN antibody, MBXL antibody, Muscleblind like 3 antibody, Muscleblind like protein 3 antibody, Muscleblind like splicing regulator 3 antibody, Muscleblind like X linked protein antibody, Muscleblind-like protein 3 antibody, Muscleblind-like X-linked protein antibody, OTTMUSP00000019072 antibody, OTTMUSP00000019073 antibody, OTTMUSP00000019074 antibody, Protein HCHCR antibody, RP23-98P13.1 antibody

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development