SGSH Antikörper (AA 273-502)
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- Target Alle SGSH Antikörper anzeigen
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
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Bindungsspezifität
- AA 273-502
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SGSH Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human N-sulphoglucosamine sulphohydrolase protein (273-502AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SGSH Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
- Andere Bezeichnung
- SGSH (SGSH Produkte)
- Synonyme
- HSS antikoerper, MPS3A antikoerper, SFMD antikoerper, 4632406A19Rik antikoerper, N-sulfoglucosamine sulfohydrolase antikoerper, N-sulfoglucosamine sulfohydrolase (sulfamidase) antikoerper, SGSH antikoerper, Sgsh antikoerper
- Hintergrund
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Background: SGSH(N-sulphoglucosamine sulphohydrolase) is also named as HSS, sulphamidase and belongs to the sulfatase family. Sulfamidase is synthesized as a 62 kDa precursor protein, which is modified with mannose 6-phosphate (M6P) residues, allowing their recognition by mannose-6-phosphate receptors in the Golgi complex and ensuring transport to the endosomal/lysosomal system. It catalyzes the third step of degradation of glucosaminoglycans and is required for the degradation of heparan sulphate. Defects in SGSH are the cause of mucopolysaccharidosis type 3A (MPS3A), also known as Sanfilippo syndrome A.
Aliases: Heparan sulfate sulfatase antibody, Heparan sulphate sulphatase antibody, HSS antibody, MPS 3A antibody, MPS3 A antibody, MPS3A antibody, Mucopolysaccharidosis type IIIA antibody, N sulfoglucosamine sulfohydrolase (sulfamidase) antibody, N sulfoglucosamine sulfohydrolase antibody, N-sulphoglucosamine sulphohydrolase antibody, SFMD antibody, SGSH antibody, SPHM_HUMAN antibody, Sulfoglucosamine sulfamidase antibody, Sulphamidase antibody, Sulphoglucosamine sulphamidase antibody
- UniProt
- P51688
- Pathways
- Glycosaminoglycan Metabolic Process
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