METTL14 Antikörper (AA 24-206)

Produktnummer ABIN7160801

Produktdetails anti-METTL14 Antikörper

Target: METTL14 (Methyltransferase Like 14 (METTL14))

Bindungsspezifität: AA 24-206

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL14 Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu METTL14

Target: METTL14 (Methyltransferase Like 14 (METTL14))

Andere Bezeichnung: METTL14 (METTL14 Produkte)

Synonyme: RGD1304822 antikoerper, G430022H21Rik antikoerper, mKIAA1627 antikoerper, zgc:77296 antikoerper, methyltransferase like 14 antikoerper, methyltransferase like 14 L homeolog antikoerper, Mettl14 antikoerper, mettl14.L antikoerper, METTL14 antikoerper, mettl14 antikoerper

Hintergrund:

Background: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5\'-[AG]GAC-3\' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).

Aliases: KIAA1627 antibody, MET14_HUMAN antibody, Methyltransferase like 14 antibody, Methyltransferase-like protein 14 antibody, METTL14 antibody, N6-adenosine-methyltransferase subunit METTL14 antibody, OTTHUMP00000219837 antibody

UniProt: Q9HCE5