NLRP1 Antikörper (AA 589-655)

Produktnummer ABIN7160821

Produktdetails anti-NLRP1 Antikörper

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Bindungsspezifität: AA 589-655

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human NACHT, LRR and PYD domains-containing protein 10 protein (589-655AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Andere Bezeichnung: NLRP1 (NLRP1 Produkte)

Synonyme: CARD7 antikoerper, CIDED antikoerper, CLR17.1 antikoerper, DEFCAP antikoerper, DEFCAP-L/S antikoerper, NAC antikoerper, NALP1 antikoerper, PP1044 antikoerper, SLEV1 antikoerper, VAMAS1 antikoerper, NLR family pyrin domain containing 1 antikoerper, NLRP1 antikoerper, Nlrp1 antikoerper

Hintergrund:

Background: Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.

Aliases: CLR11.1 antibody, NACHT, leucine rich repeat and PYD containing 10 antibody, NACHT, LRR and PYD domains containing protein 10 antibody, NACHT, LRR and PYD domains-containing protein 10 antibody, NAL10_HUMAN antibody, NALP10 antibody, NLR family, pyrin domain containing 10 antibody, Nlrp10 antibody, NOD8 antibody, Nucleotide-binding oligomerization domain protein 8 antibody, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10 antibody, PAN5 antibody, PYNOD antibody

UniProt: Q86W26

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome