NCR3 Antikörper (AA 19-135)

Produktnummer ABIN7161080

Produktdetails anti-NCR3 Antikörper

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Bindungsspezifität: AA 19-135

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Natural cytotoxicity triggering receptor 3 protein (19-135AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NCR3 (NCR3 Produkte)

Synonyme: MGC133750 antikoerper, 1C7 antikoerper, CD337 antikoerper, LY117 antikoerper, MALS antikoerper, NKp30 antikoerper, Nkp30 antikoerper, natural cytotoxicity triggering receptor 3 antikoerper, NCR3 antikoerper, Ncr3 antikoerper

Hintergrund:

Background: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Aliases: 1C7 antibody, Activating natural killer receptor p30 antibody, Activating NK A1 receptor antibody, CD337 antibody, CD337 antigen antibody, LY117 antibody, Lymphocyte antigen 117 antibody, MALS antibody, Natural cytotoxicity triggering receptor 3 antibody, Natural killer cell p30 related protein antibody, Natural killer cell p30-related protein antibody, Ncr3 antibody, NCTR3_HUMAN antibody, NK-p30 antibody, NKp30 antibody

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process