nectin-3 Antikörper (AA 310-549)
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- Target Alle nectin-3 (NECTIN3) Antikörper anzeigen
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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Bindungsspezifität
- AA 310-549
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser nectin-3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Nectin-3 protein (310-549AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NECTIN3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Andere Bezeichnung
- NECTIN3 (NECTIN3 Produkte)
- Synonyme
- PVRL3 antikoerper, CD113 antikoerper, CDW113 antikoerper, NECTIN-3 antikoerper, PPR3 antikoerper, PRR3 antikoerper, PVRR3 antikoerper, 2610301B19Rik antikoerper, 3000002N23Rik antikoerper, 4921513D19Rik antikoerper, AA407785 antikoerper, AU016832 antikoerper, AW538082 antikoerper, nectin cell adhesion molecule 3 antikoerper, poliovirus receptor-related 3 antikoerper, Nectin3 antikoerper, NECTIN3 antikoerper, PVRL3 antikoerper, nectin3 antikoerper
- Hintergrund
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Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Aliases: CD113 antibody, CDw113 antibody, DKFZP566B0846 antibody, FLJ90624 antibody, Nectin-3 antibody, Nectin3 antibody, Poliovirus receptor related 3 antibody, Poliovirus receptor related protein 3 antibody, Poliovirus receptor-like 3 antibody, Poliovirus receptor-related protein 3 antibody, PPR3 antibody, PRR3 antibody, Pvrl3 antibody, PVRL3_HUMAN antibody, PVRR3 antibody
- UniProt
- Q9NQS3
- Pathways
- Cell-Cell Junction Organization
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