NAE1 Antikörper (Regulatory Subunit)
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- Target Alle NAE1 Antikörper anzeigen
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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Bindungsspezifität
- AA 1-220, Regulatory Subunit
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NAE1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human NEDD8-activating enzyme E1 regulatory subunit protein (1-220AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NAE1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
- Andere Bezeichnung
- NAE1 (NAE1 Produkte)
- Synonyme
- APPBP1 antikoerper, CG7828 antikoerper, Dmel\\CG7828 antikoerper, anon-WO0140519.225 antikoerper, dAPP-BP1 antikoerper, dAPPBP1 antikoerper, A-116A10.1 antikoerper, ula-1 antikoerper, Appbp1 antikoerper, 59kDa antikoerper, appbp1 antikoerper, zgc:66148 antikoerper, beta-Amyloid precursor protein binding protein 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 S homeolog antikoerper, nedd8 activating enzyme E1 subunit 1 antikoerper, NEDD8-activating enzyme E1 regulatory subunit antikoerper, APP-BP1 antikoerper, NAE1 antikoerper, Nae1 antikoerper, nae1.S antikoerper, nae1 antikoerper, ula-1 antikoerper
- Hintergrund
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Background: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Aliases: 59 kDa antibody, A 116A10.1 antibody, Amyloid beta precursor protein binding protein 1 59kD antibody, Amyloid beta precursor protein binding protein 1 59 kDa antibody, Amyloid beta precursor protein binding protein 1 antibody, Amyloid beta precursor protein binding protein 1, 59 kDa antibody, Amyloid beta precursor protein-binding protein 1 antibody, Amyloid protein binding protein 1 antibody, Amyloid protein-binding protein 1 antibody, APP BP1 antibody, APP-BP1 antibody, APPBP 1 antibody, APPBP1 antibody, HPP 1 antibody, HPP1 antibody, NAE 1 antibody, NAE1 antibody, NEDD8 activating enzyme E1 regulatory subunit antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, Proto oncogene protein 1 antibody, Proto-oncogene protein 1 antibody, Protooncogene protein 1 antibody, ula 1 antibody, ULA1_HUMAN antibody
- UniProt
- Q13564
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