C19orf46 Antikörper (AA 1-242) (Biotin)

Produktnummer ABIN7161175

Produktdetails anti-C19orf46 Antikörper (Biotin)

Target: C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))

Bindungsspezifität: AA 1-242

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C19orf46 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Nesprin-4 protein (1-242AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu C19orf46

Target: C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))

Andere Bezeichnung: SYNE4 (C19orf46 Produkte)

Synonyme: C19orf46 antikoerper, Nesp4 antikoerper, C18H19orf46 antikoerper, 0610012K07Rik antikoerper, AI428936 antikoerper, RGD1304580 antikoerper, C1H19orf46 antikoerper, spectrin repeat containing nuclear envelope family member 4 antikoerper, spectrin repeat containing, nuclear envelope family member 4 antikoerper, SYNE4 antikoerper, Syne4 antikoerper

Hintergrund:

Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.

Aliases: SYNE4 antibody, C19orf46 antibody, Nesprin-4 antibody, KASH domain-containing protein 4 antibody, KASH4 antibody, Nuclear envelope spectrin repeat protein 4 antibody

UniProt: Q8N205