NEUROD2 Antikörper (AA 254-339) (HRP)

Produktnummer ABIN7161289

Produktdetails anti-NEUROD2 Antikörper (HRP)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Bindungsspezifität: AA 254-339

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEUROD2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Neurogenic differentiation factor 2 protein (254-339AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Andere Bezeichnung: NEUROD2 (NEUROD2 Produkte)

Hintergrund:

Background: Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation, prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections, involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).

Aliases: bHLHa1 antibody, class A basic helix loop helix protein 1 antibody, Class A basic helix-loop-helix protein 1 antibody, NDF2_HUMAN antibody, NDR2 antibody, NDRF antibody, neuroD related factor antibody, NeuroD-related factor antibody, NeuroD2 antibody, neurogenic basic helix loop helix protein antibody, neurogenic differentiation 2 antibody, Neurogenic differentiation factor 2 antibody, neuronal differentiation 2 antibody

UniProt: Q15784