NOTCH2 Antikörper (AA 59-250)
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- Target Alle NOTCH2 Antikörper anzeigen
- NOTCH2 (Notch 2 (NOTCH2))
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Bindungsspezifität
- AA 59-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOTCH2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Neurogenic locus notch homolog protein 2 protein (59-250AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH2 Primärantikörper
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anti-Notch 2 (NOTCH2) (N-Term) antibody
NOTCH2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Asp1733), (cleaved) antibodyNOTCH2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (C-Term) antibodyNOTCH2 Reaktivität: Human, Maus WB, ChIP-seq Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Cleaved-Asp1733) antibodyNOTCH2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2251-2466) antibodyNOTCH2 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 1501-1700) antibodyNOTCH2 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2242-2471) antibodyNOTCH2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Cleaved-Ala1734) antibodyNOTCH2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Cleaved-Ala1734), (Internal Region) antibodyNOTCH2 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 27-136) antibodyNOTCH2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NOTCH2 (Notch 2 (NOTCH2))
- Andere Bezeichnung
- NOTCH2 (NOTCH2 Produkte)
- Synonyme
- AGS2 antikoerper, HJCYS antikoerper, hN2 antikoerper, AI853703 antikoerper, N2 antikoerper, notch6 antikoerper, sb:cb884 antikoerper, neurogenic locus notch homolog protein 2 antikoerper, notch 2 antikoerper, notch 3 antikoerper, LOC581186 antikoerper, NOTCH2 antikoerper, notch3 antikoerper, Notch2 antikoerper, notch2 antikoerper
- Hintergrund
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Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells (PubMed:25985737).
Aliases: AGS2 antibody, hN2 antibody, Motch B antibody, N2 antibody, N2ECD antibody, N2ICD antibody, neurogenic locus notch homolog protein 2 antibody, NOTC2_HUMAN antibody, Notch 2 antibody, Notch 2 intracellular domain antibody, Notch Drosophila homolog 2 antibody, Notch homolog 2 antibody, Notch homolog 2 Drosophila antibody, Notch2 antibody
- UniProt
- Q04721
- Pathways
- Notch Signalweg, Stem Cell Maintenance
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