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ASAH2 Antikörper (AA 255-506) (HRP)

ASAH2 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7161489
  • Target Alle ASAH2 Antikörper anzeigen
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 255-506
    Reaktivität
    • 32
    • 14
    • 5
    Human
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASAH2 Antikörper ist konjugiert mit HRP
    Applikation
    • 20
    • 20
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Neutral ceramidase protein (255-506AA)
    Isotyp
    IgG
    Top Product
    Discover our top product ASAH2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Andere Bezeichnung
    ASAH2 (ASAH2 Produkte)
    Synonyme
    BCDase antikoerper, HNAC1 antikoerper, LCDase antikoerper, N-CDase antikoerper, NCDase antikoerper, AI585898 antikoerper, N-acylsphingosine amidohydrolase 2 antikoerper, ASAH2 antikoerper, Asah2 antikoerper
    Hintergrund

    Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

    Aliases: Acylsphingosine deacylase 2 antibody, AI585898 antibody, ASAH2 antibody, ASAH2_HUMAN antibody, BCDase antibody, hCD antibody, HNAC1 antibody, LCDase antibody, MGC129777 antibody, mitochondrial ceramidase antibody, N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody, N acylsphingosine amidohydrolase 2 antibody, N CDase antibody, N-acylsphingosine amidohydrolase 2 antibody, N-CDase antibody, NCDase antibody, Neutral ceramidase soluble form antibody, Non lysosomal ceramidase antibody, Non-lysosomal ceramidase antibody

    UniProt
    Q9NR71
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