NAMPT Antikörper (AA 1-280)

Produktnummer ABIN7161572

Produktdetails anti-NAMPT Antikörper

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Bindungsspezifität: AA 1-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Nicotinamide phosphoribosyltransferase protein (1-280AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: NAMPT (NAMPT Produkte)

Hintergrund:

Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression .

Aliases: 1110035O14Rik antibody, AI314458 antibody, AI480535 antibody, DKFZP666B131 antibody, EC 2.4.2.12 antibody, MGC117256 antibody, NAmPRTase antibody, Nampt antibody, NAMPT_HUMAN antibody, Nicotinamide phosphoribosyltransferase antibody, PBEF 1 antibody, PBEF antibody, PBEF1 antibody, Pre B cell colony enhancing factor 1 antibody, Pre B cell colony enhancing factor antibody, Pre B cell enhancing factor antibody, Pre-B cell-enhancing factor antibody, Pre-B-cell colony-enhancing factor 1 antibody, VF antibody, Visfatin antibody

UniProt: P43490