NUDT15 Antikörper (AA 1-164) (Biotin)
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- Target Alle NUDT15 Antikörper anzeigen
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
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Bindungsspezifität
- AA 1-164
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NUDT15 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Nucleotide triphosphate diphosphatase NUDT15 protein (1-164AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NUDT15 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- Andere Bezeichnung
- NUDT15 (NUDT15 Produkte)
- Synonyme
- MTH2 antikoerper, RP11-90M2.1 antikoerper, 6530403O17 antikoerper, A730068G11Rik antikoerper, nudix hydrolase 15 antikoerper, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antikoerper, NUDT15 antikoerper, Nudt15 antikoerper
- Hintergrund
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Background: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956).
Aliases: 8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, 8-oxo-dGTPase NUDT15 antibody, A730068G11Rik antibody, EC 3.1.6.- antibody, FLJ10956 antibody, MGC104352 antibody, MTH2 antibody, MutT homolog 2 antibody, Nucleoside diphosphate-linked moiety X motif 15 antibody, NUD15_HUMAN antibody, Nudix (nucleoside diphosphate linked moiety X)-type motif antibody, Nudix motif 15 antibody, NUDT15 antibody, OTTHUMP00000018389 antibody, Probable 7 antibody, Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, RP11-90M2.1 antibody
- UniProt
- Q9NV35
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