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MACROD1 Antikörper (AA 83-325)

MACROD1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7162103
  • Target Alle MACROD1 Produkte
    MACROD1 (MACRO Domain Containing 1 (MACROD1))
    Bindungsspezifität
    • 4
    • 1
    • 1
    AA 83-325
    Reaktivität
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 2
    • 2
    • 1
    • 1
    Dieser MACROD1 Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MACROD1 (MACRO Domain Containing 1 (MACROD1))
    Andere Bezeichnung
    MACROD1 (MACROD1 Produkte)
    Synonyme
    lrp16 antikoerper, d930010j01rik antikoerper, LRP16 antikoerper, AI604841 antikoerper, AW743046 antikoerper, D930010J01Rik antikoerper, Lrp16 antikoerper, MACRO domain containing 1 antikoerper, MACRO domain containing 1 L homeolog antikoerper, MACROD1 antikoerper, macrod1 antikoerper, macrod1.L antikoerper, Macrod1 antikoerper
    Hintergrund

    Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.

    Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody

    UniProt
    Q9BQ69
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