MACROD1 Antikörper (AA 83-325) (FITC)
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- Target Alle MACROD1 Produkte
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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Bindungsspezifität
- AA 83-325
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MACROD1 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
- Isotyp
- IgG
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
- Andere Bezeichnung
- MACROD1 (MACROD1 Produkte)
- Synonyme
- lrp16 antikoerper, d930010j01rik antikoerper, LRP16 antikoerper, AI604841 antikoerper, AW743046 antikoerper, D930010J01Rik antikoerper, Lrp16 antikoerper, MACRO domain containing 1 antikoerper, MACRO domain containing 1 L homeolog antikoerper, MACROD1 antikoerper, macrod1 antikoerper, macrod1.L antikoerper, Macrod1 antikoerper
- Hintergrund
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Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody
- UniProt
- Q9BQ69
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