PASK Antikörper (AA 482-602)

Produktnummer ABIN7162684

Produktdetails anti-PASK Antikörper

Target: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Bindungsspezifität: AA 482-602

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PASK Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human PAS domain-containing serine/threonine-protein kinase protein (482-602AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PASK

Target: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Andere Bezeichnung: PASK (PASK Produkte)

Synonyme: pas antikoerper, wu:fb69h07 antikoerper, PASK antikoerper, PASKIN antikoerper, STK37 antikoerper, mKIAA0135 antikoerper, PAS domain containing serine/threonine kinase antikoerper, Pask antikoerper, pask antikoerper, PASK antikoerper

Hintergrund:

Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Aliases: DKFZP434O051 antibody, DKFZp686P2031 antibody, hPASK antibody, KIAA0135 antibody, MGC93882 antibody, mKIAA0135 antibody, PAS domain containing serine/threonine kinase antibody, PAS domain containing serine/threonine protein kinase antibody, PAS domain-containing serine/threonine-protein kinase antibody, PAS kinase antibody, PAS serine/threonine kinase antibody, PAS-kinase antibody, Pask antibody, PASK_HUMAN antibody, PASKIN antibody, STK 37 antibody, STK37 antibody

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process