PREX1 Antikörper (AA 1-44)

Produktnummer ABIN7163177

Produktdetails anti-PREX1 Antikörper

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Bindungsspezifität: AA 1-44

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Andere Bezeichnung: PREX1 (PREX1 Produkte)

Synonyme: MGC68772 antikoerper, P-REX1 antikoerper, G630042G04 antikoerper, Setd6 antikoerper, RGD1306534 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antikoerper, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antikoerper, prex1.L antikoerper, PREX1 antikoerper, prex1 antikoerper, Prex1 antikoerper

Hintergrund:

Background: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Aliases: 4 antibody, 5)-dependent Rac exchanger 1 antibody, KIAA1415 antibody, OTTHUMP00000031228 antibody, P REX1 antibody, P Rex1 protein like antibody, P-Rex1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody, Prex1 antibody, PREX1_HUMAN antibody, PtdIns(3 antibody, PtdIns(3,4,5) dependent Rac exchanger 1 antibody, SET domain containing 6 antibody, Setd6 antibody

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization