PIK3AP1 Antikörper (AA 293-404)

Produktnummer ABIN7163287

Produktdetails anti-PIK3AP1 Antikörper

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Bindungsspezifität: AA 293-404

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3AP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PIK3AP1

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Andere Bezeichnung: PIK3AP1 (PIK3AP1 Produkte)

Synonyme: BCAP antikoerper, RP11-34E5.3 antikoerper, 1810044J04Rik antikoerper, phosphoinositide-3-kinase adaptor protein 1 antikoerper, PIK3AP1 antikoerper, Pik3ap1 antikoerper

Hintergrund:

Background: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

Aliases: PIK3AP1 antibody, BCAPPhosphoinositide 3-kinase adapter protein 1 antibody, B-cell adapter for phosphoinositide 3-kinase antibody, B-cell phosphoinositide 3-kinase adapter protein 1 antibody

UniProt: Q6ZUJ8

Pathways: Activation of Innate immune Response, BCR Signaling, Warburg Effekt