PIK3R6 Antikörper (Regulatory Subunit 6)
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- Target Alle PIK3R6 Antikörper anzeigen
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
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Bindungsspezifität
- AA 566-667, Regulatory Subunit 6
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PIK3R6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
- Andere Bezeichnung
- PIK3R6 (PIK3R6 Produkte)
- Synonyme
- C17orf38 antikoerper, HsT41028 antikoerper, p84 antikoerper, p84 PIKAP antikoerper, p87(PIKAP) antikoerper, p87PIKAP antikoerper, BB220380 antikoerper, RGD1560850 antikoerper, phosphoinositide-3-kinase regulatory subunit 6 antikoerper, phosphoinositide-3-kinase regulatory subunit 5 antikoerper, phosphoinositide-3-kinase, regulatory subunit 6 antikoerper, PIK3R6 antikoerper, Pik3r6 antikoerper
- Hintergrund
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Background: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.
Aliases: C17orf38 antibody, Chromosome 17 open reading frame 38 antibody, HsT41028 antibody, p84 PI3K adapter protein antibody, p84 PIKAP antibody, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein antibody, p87 PI3K adapter protein antibody, p87PIKAP antibody, Phosphatidylinositol 3-kinase, regulatory subunit 6 antibody, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa antibody, Phosphoinositide 3-kinase regulatory subunit 6 antibody, PI3Kgamma adapter protein of 87 kDa antibody, PI3R6_HUMAN antibody, PIK3R6 antibody
- UniProt
- Q5UE93
- Pathways
- PI3K-Akt Signalweg, Inositol Metabolic Process
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