PAG1 Antikörper (AA 97-432) (FITC)

Produktnummer ABIN7163393

Produktdetails anti-PAG1 Antikörper (FITC)

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Bindungsspezifität: AA 97-432

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAG1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein (97-432AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PAG1

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Andere Bezeichnung: PAG1 (PAG1 Produkte)

Hintergrund:

Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Aliases: CBP antibody, Csk binding protein antibody, Csk-binding protein antibody, FLJ37858 antibody, MGC138364 antibody, PAG 1 antibody, PAG antibody, PAG1 antibody, PAG1_HUMAN antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains antibody, Phosphoprotein associated with glycosphingolipid microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 antibody, Protein Associated with Glycosphingolipid Enriched Microdomains antibody, Transmembrane adapter protein PAG antibody, Transmembrane phosphoprotein Cbp antibody

UniProt: Q9NWQ8

Pathways: p53 Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events