PHLDA3 Antikörper (AA 43-95) (HRP)
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- Target Alle PHLDA3 Antikörper anzeigen
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Bindungsspezifität
- AA 43-95
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PHLDA3 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
- Isotyp
- IgG
- Top Product
- Discover our top product PHLDA3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
- Andere Bezeichnung
- PHLDA3 (PHLDA3 Produkte)
- Synonyme
- TIH1 antikoerper, Tih1 antikoerper, si:dz182n13.5 antikoerper, zgc:92333 antikoerper, pleckstrin homology like domain family A member 3 antikoerper, pleckstrin homology like domain, family A, member 3 antikoerper, pleckstrin homology-like domain, family A, member 3 antikoerper, PHLDA3 antikoerper, Phlda3 antikoerper, phlda3 antikoerper
- Hintergrund
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Background: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Aliases: PHLA3_HUMAN antibody, PHLDA 3 antibody, phlda3 antibody, Pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology like domain family A member 3 antibody, Pleckstrin homology-like domain family A member 3 antibody, TDAG51/Ipl homolog 1 antibody, TDAG51/Ipl homologue 1 antibody, TIH 1 antibody, TIH1 antibody
- UniProt
- Q9Y5J5
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