Plexin B2 Antikörper (AA 1080-1200)

Produktnummer ABIN7163708

Produktdetails anti-Plexin B2 Antikörper

Target: Plexin B2 (PLXNB2)

Bindungsspezifität: AA 1080-1200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plexin B2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Plexin-B2 protein (1080-1200AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Plexin B2

Target: Plexin B2 (PLXNB2)

Andere Bezeichnung: PLXNB2 (PLXNB2 Produkte)

Synonyme: PLXNB2 antikoerper, MM1 antikoerper, Nbla00445 antikoerper, PLEXB2 antikoerper, dJ402G11.3 antikoerper, 1110007H23Rik antikoerper, Debt antikoerper, mKIAA0315 antikoerper, plexin B2 antikoerper, plexin B2 S homeolog antikoerper, PLXNB2 antikoerper, plxnb2.S antikoerper, plxnb2 antikoerper, Plxnb2 antikoerper

Hintergrund:

Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody

UniProt: O15031

Pathways: Tube Formation