PARP2 Antikörper (AA 14-149)

Produktnummer ABIN7163747

Produktdetails anti-PARP2 Antikörper

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Bindungsspezifität: AA 14-149

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Poly [ADP-ribose] polymerase 2 protein (14-149AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Andere Bezeichnung: PARP2 (PARP2 Produkte)

Synonyme: ADPRT2 antikoerper, ADPRTL2 antikoerper, ADPRTL3 antikoerper, ARTD2 antikoerper, PARP-2 antikoerper, pADPRT-2 antikoerper, Adprt2 antikoerper, Adprtl2 antikoerper, Aspartl2 antikoerper, C78626 antikoerper, cb996 antikoerper, adprtl2 antikoerper, ADPRT-2 antikoerper, APP antikoerper, ATPARP1 antikoerper, PARP1 antikoerper, POLY(ADP-RIBOSE) POLYMERASE antikoerper, POLY(ADP-RIBOSE) POLYMERASE 1 antikoerper, PP antikoerper, T14P8.19 antikoerper, T14P8_19 antikoerper, poly(ADP-ribose) polymerase antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly (ADP-ribose) polymerase family, member 2 antikoerper, poly (ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 S homeolog antikoerper, poly(ADP-ribose) polymerase antikoerper, PARP2 antikoerper, Parp2 antikoerper, parp2 antikoerper, parp2.S antikoerper

Hintergrund:

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).

Aliases: ADP ribosyltransferase like 2 antibody, ADP-ribosyltransferase diphtheria toxin-like 2 antibody, ADPRT 2 antibody, ADPRT-2 antibody, ADPRT2 antibody, ADPRTL 2 antibody, ADPRTL 3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD2 antibody, hPARP 2 antibody, hPARP-2 antibody, hPARP2 antibody, NAD(+) ADP ribosyltransferase 2 antibody, NAD(+) ADP-ribosyltransferase 2 antibody, pADPRT 2 antibody, pADPRT-2 antibody, pADPRT2 antibody, PARP 2 antibody, PARP-2 antibody, PARP2 antibody, PARP2_HUMAN antibody, Poly (ADP ribose) polymerase family member 2 antibody, Poly (ADP ribosyl) transferase like 2 antibody, poly (ADP-ribose) polymerase 2 antibody, Poly [ADP ribose] synthetase 2 antibody, Poly [ADP-ribose] polymerase 2 antibody, Poly(ADP ribose) synthetase antibody, Poly[ADP-ribose] synthase 2 antibody

UniProt: Q9UGN5

Pathways: DNA Reparatur