EED Antikörper (AA 1-300)

Produktnummer ABIN7163806

Produktdetails anti-EED Antikörper

Target: EED (Embryonic Ectoderm Development (EED))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Polycomb protein EED protein (1-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED (EED Produkte)

Synonyme: Xeed antikoerper, heed antikoerper, wait1 antikoerper, EED antikoerper, HEED antikoerper, WAIT1 antikoerper, zgc:112509 antikoerper, Xeed-B antikoerper, eed antikoerper, psXEED antikoerper, ENSMUSG00000039373 antikoerper, l(7)5Rn antikoerper, l7Rn5 antikoerper, lusk antikoerper, Xeed-A antikoerper, embryonic ectoderm development antikoerper, embryonic ectoderm development S homeolog antikoerper, microRNA 6755 antikoerper, embryonic ectoderm development L homeolog antikoerper, eed antikoerper, EED antikoerper, eed.S antikoerper, MIR6755 antikoerper, Eed antikoerper, eed.L antikoerper

Hintergrund:

Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates \\\'Lys-9\\\' and \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes \\\'Lys-26\\\' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 \\\'Lys-27\\\', whereas H3 \\\'Lys-27\\\' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Aliases: eed antibody, EED protein antibody, EED, mouse, homolog of antibody, EED_HUMAN antibody, Embryonic ectoderm development antibody, Embryonic ectoderm development isoform a antibody, Embryonic ECTODERM development protein homolog antibody, Embryonic ectoderm development protein, mouse, homolog of antibody, hEED antibody, OTTHUMP00000235483 antibody, OTTHUMP00000235484 antibody, OTTHUMP00000235485 antibody, Polycomb protein eed antibody, WAIT 1 antibody, WAIT-1 antibody, WAIT1 antibody, WD protein associating with integrin cytoplasmic tails 1 antibody

UniProt: O75530