WTAP Antikörper (AA 1-151) (HRP)

Produktnummer ABIN7164197

Produktdetails anti-WTAP Antikörper (HRP)

Target: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Bindungsspezifität: AA 1-151

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WTAP Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WTAP

Target: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Andere Bezeichnung: WTAP (WTAP Produkte)

Synonyme: MGC75954 antikoerper, WTAP antikoerper, RGD1563824 antikoerper, wu:fi29a09 antikoerper, zgc:66202 antikoerper, 2810408K05Rik antikoerper, 9430038B09Rik antikoerper, WT1 associated protein antikoerper, Wilms tumor 1 associated protein antikoerper, wilms tumor 1 associated protein antikoerper, WT1 associated protein L homeolog antikoerper, Wilms tumour 1-associating protein antikoerper, wtap antikoerper, WTAP antikoerper, CpipJ_CPIJ006489 antikoerper, Wtap antikoerper, wtap.L antikoerper

Hintergrund:

Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3\' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).

Aliases: DKFZp686F20131 antibody, Female-lethal(2)D homolog antibody, FL2D_HUMAN antibody, hFL(2)D antibody, KIAA0105 antibody, MGC3925 antibody, Mum2 antibody, OTTHUMP00000017522 antibody, OTTHUMP00000017523 antibody, PNAS 132 antibody, PNAS-132 antibody, PNAS132 antibody, Pre mRNA splicing regulator WTAP antibody, Pre-mRNA-splicing regulator WTAP antibody, Putative pre mRNA splicing regulator female lethal 2D homolog antibody, Putative pre mRNA splicing regulator female lethal(2D) antibody, Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody, putative pre-mRNA splicing regulator female-lethal(2D) antibody, Wilms tumor 1 associated protein antibody, Wilms tumor 1 associating protein antibody, Wilms tumor 1-associating protein antibody, Wilms' tumor 1 associating protein antibody, Wilms' tumour 1-associating protein antibody, WT1 associated protein antibody, WT1-associated protein antibody, WT1-associating protein antibody, wtap antibody

UniProt: Q15007