PITRM1 Antikörper (AA 758-1037)

Produktnummer ABIN7164274

Produktdetails anti-PITRM1 Antikörper

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Bindungsspezifität: AA 758-1037

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PITRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Presequence protease, mitochondrial protein (758-1037AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Andere Bezeichnung: PITRM1 (PITRM1 Produkte)

Synonyme: MP1 antikoerper, PreP antikoerper, 2310012C15Rik antikoerper, AA410010 antikoerper, MP-1 antikoerper, Ntup1 antikoerper, mKIAA1104 antikoerper, PITRM1 antikoerper, wu:fa03d09 antikoerper, zgc:55469 antikoerper, pitrilysin metallopeptidase 1 antikoerper, pitrilysin metallepetidase 1 antikoerper, pitrilysin metallopeptidase 1 L homeolog antikoerper, PITRM1 antikoerper, Pitrm1 antikoerper, pitrm1.L antikoerper, pitrm1 antikoerper

Hintergrund:

Background: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Aliases: hMP1 antibody, hPreP antibody, KIAA1104 antibody, Metalloprotease 1 antibody, MGC138192 antibody, MGC141929 antibody, mitochondrial antibody, MP1 antibody, Pitrilysin metallopeptidase 1 antibody, Pitrilysin metalloproteinase 1 antibody, PITRM 1 antibody, PITRM1 antibody, PreP antibody, PreP peptidasome antibody, PREP_HUMAN antibody, Presequence protease antibody, Presequence protease mitochondrial antibody

UniProt: Q5JRX3

Pathways: PI3K-Akt Signalweg, SARS-CoV-2 Protein Interaktom