HBEGF Antikörper (AA 63-148)

Produktnummer ABIN7164700

Produktdetails anti-HBEGF Antikörper

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Bindungsspezifität: AA 63-148

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBEGF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Proheparin-binding EGF-like growth factor protein (63-148AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Andere Bezeichnung: HBEGF (HBEGF Produkte)

Hintergrund:

Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Aliases: diphtheria toxin receptor (heparin-binding EGF-like growth factor) antibody, diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) antibody, Diphtheria toxin receptor antibody, DT R antibody, DT-R antibody, DTR antibody, DTS antibody, DTSF antibody, HB-EGF antibody, HBEGF antibody, HBEGF_HUMAN antibody, HEGFL antibody, Heparin binding EGF like growth factor antibody, Heparin binding epidermal growth factor antibody, Heparin binding epidermal growth factor like growth factor antibody, Heparin-binding EGF-like growth factor antibody, Proheparin binding EGF like growth factor antibody

UniProt: Q99075

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung