PRMT7 Antikörper (AA 285-390)

Produktnummer ABIN7165083

Der Kaninchen Polyklonal Anti-PRMT7-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, PRMT7 in Proben von Human zu detektieren.

Kurzübersicht für PRMT7 Antikörper (AA 285-390) (ABIN7165083)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PRMT7 Antikörper

Bindungsspezifität: AA 285-390

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein arginine N-methyltransferase 7 protein (285-390AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Andere Bezeichnung: PRMT7

Hintergrund:

Background: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 \\\'Arg-3\\\' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.

Aliases: [Myelin basic protein]-arginine N-methyltransferase PRMT7 antibody, ANM7_HUMAN antibody, FLJ10640 antibody, Histone-arginine N-methyltransferase PRMT7 antibody, KIAA1933 antibody, Myelin basic protein arginine N methyltransferase antibody, OTTHUMP00000174863 antibody, PRMT7 antibody, Protein arginine methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization