HOOK3 Antikörper (AA 357-455)

Produktnummer ABIN7165641

Produktdetails anti-HOOK3 Antikörper

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Bindungsspezifität: AA 357-455

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOOK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein Hook homolog 3 protein (357-455AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HOOK3

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Andere Bezeichnung: HOOK3 (HOOK3 Produkte)

Synonyme: 5830454D03Rik antikoerper, AI317159 antikoerper, E330005F07Rik antikoerper, HK3 antikoerper, hook3 antikoerper, hook microtubule-tethering protein 3 antikoerper, hook microtubule tethering protein 3 antikoerper, hook microtubule-tethering protein 3 L homeolog antikoerper, Hook3 antikoerper, HOOK3 antikoerper, hook3.L antikoerper

Hintergrund:

Background: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).

Aliases: FLJ31058 antibody, h-hook3 antibody, hHK3 antibody, HK3 antibody, hook3 antibody, HOOK3_HUMAN antibody, OTTHUMP00000229200 antibody, Protein Hook homolog 3 antibody

UniProt: Q86VS8

Pathways: Stem Cell Maintenance, Maintenance of Protein Location