IWS1 Antikörper (AA 570-819)

Produktnummer ABIN7165661

Produktdetails anti-IWS1 Antikörper

Target: IWS1 (IWS1 Homolog (IWS1))

Bindungsspezifität: AA 570-819

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IWS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein IWS1 homolog protein (570-819AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IWS1

Target: IWS1 (IWS1 Homolog (IWS1))

Andere Bezeichnung: IWS1 (IWS1 Produkte)

Synonyme: 1700069O15Rik antikoerper, 3000008H23 antikoerper, AL117927 antikoerper, AW214353 antikoerper, RGD1304762 antikoerper, IWS1, SUPT6H interacting protein antikoerper, IWS1, SUPT6 interacting protein antikoerper, IWS1 antikoerper, Iws1 antikoerper

Hintergrund:

Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Aliases: DKFZp761G0123 antibody, FLJ10006 antibody, FLJ14655 antibody, FLJ32319 antibody, Interacts with Spt6 antibody, iws1 antibody, IWS1 homolog antibody, IWS1-like protein antibody, IWS1_HUMAN antibody, IWS1L antibody, MGC126375 antibody, MGC126376 antibody, OTTHUMP00000162262 antibody, Protein IWS1 homolog antibody

UniProt: Q96ST2