BBS9 Antikörper (AA 8-185)

Produktnummer ABIN7165997

Produktdetails anti-BBS9 Antikörper

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Bindungsspezifität: AA 8-185

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS9 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein PTHB1 protein (8-185AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BBS9

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Andere Bezeichnung: BBS9 (BBS9 Produkte)

Synonyme: b1 antikoerper, B1 antikoerper, C18 antikoerper, D1 antikoerper, PTHB1 antikoerper, RGD1308472 antikoerper, E130103I17Rik antikoerper, Bardet-Biedl syndrome 9 antikoerper, bardet-biedl syndrome 9 antikoerper, Bardet-Biedl syndrome 9 (human) antikoerper, BBS9 antikoerper, bbs9 antikoerper, Bbs9 antikoerper

Hintergrund:

Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

Aliases: B1 antibody, Bardet Biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 protein antibody, bbs9 antibody, C18 antibody, D1 antibody, MGC118917 antibody, OTTHUMP00000158833 antibody, OTTHUMP00000202918 antibody, OTTHUMP00000202919 antibody, OTTHUMP00000202920 antibody, Parathyroid hormone-responsive B1 gene protein antibody, Protein PTHB1 antibody, PTH-responsive osteosarcoma B1 protein antibody, PTHB1 antibody, PTHB1_HUMAN antibody

UniProt: Q3SYG4

Pathways: Hedgehog Signalweg