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SBNO2 Antikörper (AA 6-146) (FITC)

SBNO2 Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7166168
  • Target Alle SBNO2 Antikörper anzeigen
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Bindungsspezifität
    AA 6-146
    Reaktivität
    Human
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    Dieser SBNO2 Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
    Isotyp
    IgG
    Top Product
    Discover our top product SBNO2 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Andere Bezeichnung
    SBNO2 (SBNO2 Produkte)
    Synonyme
    KIAA0963 antikoerper, SNO antikoerper, STNO antikoerper, BC019206 antikoerper, F730040C21 antikoerper, Sno antikoerper, Stno antikoerper, strawberry notch homolog 2 antikoerper, strawberry notch homolog 2 (Drosophila) antikoerper, SBNO2 antikoerper, Sbno2 antikoerper
    Hintergrund

    Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

    Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody

    UniProt
    Q9Y2G9
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