UXT Antikörper (AA 1-157)
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- Target Alle UXT Antikörper anzeigen
- UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))
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Bindungsspezifität
- AA 1-157
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UXT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Protein UXT protein (1-157AA)
- Isotyp
- IgG
- Top Product
- Discover our top product UXT Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))
- Andere Bezeichnung
- UXT (UXT Produkte)
- Synonyme
- zgc:101894 antikoerper, 0910002B17Rik antikoerper, ART-27 antikoerper, STAP1 antikoerper, ubiquitously-expressed, prefoldin-like chaperone antikoerper, ubiquitously expressed prefoldin like chaperone antikoerper, ubiquitously-expressed transcript antikoerper, ubiquitously expressed transcript antikoerper, uxt antikoerper, UXT antikoerper, Uxt antikoerper
- Hintergrund
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Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.
Aliases: Androgen receptor trapped clone 27 protein antibody, ART 27 antibody, ART-27 antibody, OTTHUMP00000023226 antibody, OTTHUMP00000023227 antibody, Protein UXT antibody, SKP2 associated alpha PFD 1 antibody, STAP1 antibody, Ubiquitously expressed prefoldin like chaperone antibody, Ubiquitously expressed transcript antibody, Ubiquitously expressed transcript protein antibody, Uxt antibody, UXT_HUMAN antibody
- UniProt
- Q9UBK9
- Pathways
- Unfolded Protein Response
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