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UXT Antikörper (AA 1-157)

UXT Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7166273
  • Target Alle UXT Antikörper anzeigen
    UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))
    Bindungsspezifität
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-157
    Reaktivität
    • 23
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 20
    • 2
    • 2
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UXT Antikörper ist unkonjugiert
    Applikation
    • 16
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Protein UXT protein (1-157AA)
    Isotyp
    IgG
    Top Product
    Discover our top product UXT Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))
    Andere Bezeichnung
    UXT (UXT Produkte)
    Synonyme
    zgc:101894 antikoerper, 0910002B17Rik antikoerper, ART-27 antikoerper, STAP1 antikoerper, ubiquitously-expressed, prefoldin-like chaperone antikoerper, ubiquitously expressed prefoldin like chaperone antikoerper, ubiquitously-expressed transcript antikoerper, ubiquitously expressed transcript antikoerper, uxt antikoerper, UXT antikoerper, Uxt antikoerper
    Hintergrund

    Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.

    Aliases: Androgen receptor trapped clone 27 protein antibody, ART 27 antibody, ART-27 antibody, OTTHUMP00000023226 antibody, OTTHUMP00000023227 antibody, Protein UXT antibody, SKP2 associated alpha PFD 1 antibody, STAP1 antibody, Ubiquitously expressed prefoldin like chaperone antibody, Ubiquitously expressed transcript antibody, Ubiquitously expressed transcript protein antibody, Uxt antibody, UXT_HUMAN antibody

    UniProt
    Q9UBK9
    Pathways
    Unfolded Protein Response
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