PYHIN1 Antikörper (AA 1-245)

Produktnummer ABIN7166880

Produktdetails anti-PYHIN1 Antikörper

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Bindungsspezifität: AA 1-245

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYHIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PYHIN1

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Andere Bezeichnung: PYHIN1 (PYHIN1 Produkte)

Synonyme: IFIX antikoerper, RP11-520H16.1 antikoerper, 4930422C14 antikoerper, AI447904 antikoerper, Ifi209 antikoerper, Ifix antikoerper, pyrin and HIN domain family member 1 antikoerper, interferon activated gene 209 antikoerper, PYHIN1 antikoerper, Ifi209 antikoerper

Hintergrund:

Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.

Aliases: IFIX_HUMAN antibody, Interferon-inducible protein X antibody, Pyhin1 antibody, Pyrin and HIN domain-containing protein 1 antibody

UniProt: Q6K0P9