PKM Antikörper (AA 2-192)

Produktnummer ABIN7166912

Produktdetails anti-PKM Antikörper

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Bindungsspezifität: AA 2-192

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Pyruvate kinase PKM protein (2-192AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PKM

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Andere Bezeichnung: PKM (PKM Produkte)

Synonyme: CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, CG7070 antikoerper, Dmel\\CG7070 antikoerper, PYK antikoerper, Pyk antikoerper, cb1029 antikoerper, fj33f03 antikoerper, pkm2 antikoerper, pkm2a antikoerper, wu:fj33f03 antikoerper, MGC53388 antikoerper, PKM antikoerper, PK-S antikoerper, pk3 antikoerper, pkm2b antikoerper, zgc:92037 antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, Pyruvate kinase antikoerper, pyruvate kinase M1/2a antikoerper, pyruvate kinase PKM antikoerper, pyruvate kinase (PK) antikoerper, pyruvate kinase antikoerper, pyruvate kinase M1/2 S homeolog antikoerper, pyruvate kinase M1/2b antikoerper, PKM antikoerper, Pkm antikoerper, PyK antikoerper, pkma antikoerper, pkm antikoerper, LOC710798 antikoerper, pyk antikoerper, pk antikoerper, LOC100534543 antikoerper, pkm.S antikoerper, pkmb antikoerper

Hintergrund:

Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

Aliases: CTHBP antibody, Cytosolic thyroid hormone-binding protein antibody, KPYM_HUMAN antibody, OIP-3 antibody, Opa-interacting protein 3 antibody, p58 antibody, pkm antibody, PKM1 antibody, PKM2 antibody, Pyruvate kinase 2/3 antibody, Pyruvate kinase muscle isozyme antibody, Pyruvate kinase PKM antibody, THBP1 antibody, Thyroid hormone-binding protein 1 antibody, Tumor M2-PK antibody

UniProt: P14618

Pathways: Warburg Effekt