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QTRT1 Antikörper (Catalytic Subunit 1) (Biotin)

QTRT1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7166919
  • Target Alle QTRT1 Antikörper anzeigen
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-403, Catalytic Subunit 1
    Reaktivität
    • 35
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser QTRT1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 26
    • 17
    • 3
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
    Isotyp
    IgG
    Top Product
    Discover our top product QTRT1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Andere Bezeichnung
    QTRT1 (QTRT1 Produkte)
    Synonyme
    CG4947 antikoerper, Dmel\\CG4947 antikoerper, TGT antikoerper, tgt antikoerper, zgc:66378 antikoerper, FP3235 antikoerper, TGUT antikoerper, 2610028E17Rik antikoerper, Tgt antikoerper, Tgut antikoerper, tRNA-guanine transglycosylase antikoerper, queuine tRNA-ribosyltransferase 1 S homeolog antikoerper, queuine tRNA-ribosyltransferase 1 antikoerper, queuine tRNA-ribosyltransferase catalytic subunit 1 antikoerper, Tgt antikoerper, Olsu_0732 antikoerper, Palpr_1298 antikoerper, Riean_1227 antikoerper, Calni_1240 antikoerper, Ftrac_0312 antikoerper, Ocepr_1541 antikoerper, Sulku_0977 antikoerper, Tmar_0854 antikoerper, Bache_2323 antikoerper, Nitsa_1291 antikoerper, Isop_1657 antikoerper, Despr_0021 antikoerper, Pedsa_1842 antikoerper, Corgl_1148 antikoerper, Mahau_0921 antikoerper, Theth_0831 antikoerper, qtrt1.S antikoerper, qtrt1 antikoerper, QTRT1 antikoerper, Qtrt1 antikoerper
    Hintergrund

    Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\' of the ribose to form the product (By similarity).

    Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

    UniProt
    Q9BXR0
    Pathways
    Ribonucleoside Biosynthetic Process
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