IER3 Antikörper (AA 1-82)

Produktnummer ABIN7167054

Produktdetails anti-IER3 Antikörper

Target: IER3 (Immediate Early Response 3 (IER3))

Bindungsspezifität: AA 1-82

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IER3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IER3

Target: IER3 (Immediate Early Response 3 (IER3))

Andere Bezeichnung: IER3 (IER3 Produkte)

Synonyme: DIF-2 antikoerper, DIF2 antikoerper, GLY96 antikoerper, IEX-1 antikoerper, IEX-1L antikoerper, IEX1 antikoerper, PRG1 antikoerper, AI663993 antikoerper, cI-3 antikoerper, gly96 antikoerper, IER3 antikoerper, Dif2 antikoerper, Iex1 antikoerper, Ler3 antikoerper, Prg1 antikoerper, immediate early response 3 antikoerper, IER3 antikoerper, Ier3 antikoerper

Hintergrund:

Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

Aliases: DIF2 antibody, Differentiation-dependent gene 2 protein antibody, GLY96 antibody, IER3 antibody, IEX1_HUMAN antibody, IEX1L antibody, Immediate early protein GLY96 antibody, Immediate early response 3 antibody, Immediate early response 3 protein antibody, Immediately early gene X 1 antibody, PACAP-responsive gene 1 protein antibody, PRG 1 antibody, PRG1 antibody, Protein DIF 2 antibody, Protein DIF-2 antibody, Protein PRG1 antibody, Radiation-inducible immediate-early gene IEX-1 antibody

UniProt: P46695

Pathways: Regulation of Carbohydrate Metabolic Process