MAPKSP1 Antikörper (AA 1-124)

Produktnummer ABIN7167072

Produktdetails anti-MAPKSP1 Antikörper

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Bindungsspezifität: AA 1-124

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKSP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MAPKSP1

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Andere Bezeichnung: LAMTOR3 (MAPKSP1 Produkte)

Hintergrund:

Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Aliases: LAMTOR3 antibody, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody, LTOR3_HUMAN antibody, MAP2K1IP1 antibody, MEK binding partner 1 antibody, MEK partner 1 antibody, MEK-binding partner 1 antibody, Mitogen activated protein kinase kinase 1 interacting protein 1 antibody, Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody, Mitogen-activated protein kinase scaffold protein 1 antibody, Mp1 antibody, Ragulator complex protein LAMTOR3 antibody

UniProt: Q9UHA4

Pathways: PI3K-Akt Signalweg