RAB11B Antikörper (AA 2-215)

Produktnummer ABIN7167225

Produktdetails anti-RAB11B Antikörper

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Bindungsspezifität: AA 2-215

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB11B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-11B protein (2-215AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAB11B

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Andere Bezeichnung: RAB11B (RAB11B Produkte)

Synonyme: zgc:92772 antikoerper, H-YPT3 antikoerper, A730055L17Rik antikoerper, rab11b antikoerper, wu:fb07g11 antikoerper, zgc:55760 antikoerper, RAB11B, member RAS oncogene family, b antikoerper, RAB11B, member RAS oncogene family antikoerper, RAB11B, member RAS oncogene family, a antikoerper, RAB11B, member RAS oncogene family, gene 1 S homeolog antikoerper, rab11bb antikoerper, RAB11B antikoerper, Rab11b antikoerper, rab11ba antikoerper, rab11b.1.S antikoerper

Hintergrund:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

Aliases: GTP binding protein YPT3 antibody, GTP-binding protein ypt3 antibody, H-YPT3 antibody, RAB 11A antibody, RAB11B antibody, RAB11B member RAS oncogene family antibody, RAB11B, member of RAS oncogene family antibody, Ras related protein Rab 11B antibody, RAS-associated protein RAB11B antibody, Ras-related protein Rab-11B antibody, RB11B_HUMAN antibody, YPT3 antibody

UniProt: Q15907

Pathways: Hormone Transport, Carbohydrate Homeostasis