RAB23 Antikörper (AA 18-234) (Biotin)

Produktnummer ABIN7167255

Produktdetails anti-RAB23 Antikörper (Biotin)

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Bindungsspezifität: AA 18-234

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB23 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-23 protein (18-234aa)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAB23

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Andere Bezeichnung: RAB23 (RAB23 Produkte)

Synonyme: MGC82152 antikoerper, hspc137 antikoerper, zgc:110261 antikoerper, AW545388 antikoerper, opb antikoerper, opb2 antikoerper, HSPC137 antikoerper, Rab23-like antikoerper, RAB23, member RAS oncogene family S homeolog antikoerper, RAB23, member RAS oncogene family antikoerper, ras-related protein Rab-23 antikoerper, rab23.S antikoerper, RAB23 antikoerper, rab23 antikoerper, Rab23 antikoerper

Hintergrund:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Aliases: Ras-related protein Rab-23, RAB23

UniProt: Q9ULC3

Pathways: Tube Formation