RTEL1 Antikörper (AA 975-1219) (HRP)

Produktnummer ABIN7167651

Produktdetails anti-RTEL1 Antikörper (HRP)

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Bindungsspezifität: AA 975-1219

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTEL1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Regulator of telomere elongation helicase 1 protein (975-1219AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Andere Bezeichnung: RTEL1 (RTEL1 Produkte)

Synonyme: F18B13.3 antikoerper, F18B13_3 antikoerper, C20orf41 antikoerper, DKCB5 antikoerper, NHL antikoerper, RTEL antikoerper, bK3184A7.3 antikoerper, AI451565 antikoerper, AW540478 antikoerper, Rtel antikoerper, RGD1306721 antikoerper, zgc:113114 antikoerper, regulator of telomere elongation helicase 1 antikoerper, RAD3-like DNA-binding helicase protein antikoerper, RTEL1 antikoerper, rtel1 antikoerper, AT1G79950 antikoerper, LOC100286037 antikoerper, Rtel1 antikoerper

Hintergrund:

Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Aliases: RTEL1 antibody, C20orf41 antibody, KIAA1088 antibody, NHLRegulator of telomere elongation helicase 1 antibody, EC 3.6.4.12 antibody, Novel helicase-like antibody

UniProt: Q9NZ71