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CoREST Antikörper (AA 394-482) (HRP)

RCOR1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7167724
  • Target Alle CoREST (RCOR1) Antikörper anzeigen
    CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    AA 394-482
    Reaktivität
    • 38
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 1
    • 1
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CoREST Antikörper ist konjugiert mit HRP
    Applikation
    • 28
    • 16
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human REST corepressor 1 protein (394-482AA)
    Isotyp
    IgG
    Top Product
    Discover our top product RCOR1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
    Andere Bezeichnung
    RCOR1 (RCOR1 Produkte)
    Synonyme
    COREST antikoerper, RCOR antikoerper, 5730409O11 antikoerper, 6720480E22Rik antikoerper, AU042633 antikoerper, D12Wsu95e antikoerper, mKIAA0071 antikoerper, rcor1 antikoerper, xcoREST antikoerper, RCOR1 antikoerper, im:6904264 antikoerper, si:dkey-46n18.7 antikoerper, zgc:158607 antikoerper, RGD1305743 antikoerper, REST corepressor 1 antikoerper, REST corepressor 1 L homeolog antikoerper, RCOR1 antikoerper, Rcor1 antikoerper, rcor1.L antikoerper, rcor1 antikoerper
    Hintergrund

    Background: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.

    Aliases: COREST antibody, KIAA0071 antibody, Nr2b2 antibody, Nuclear receptor coregulator 1 antibody, Nuclear receptor subfamily 2 group B member 2 antibody, Protein CoREST antibody, RCOR antibody, Rcor1 antibody, RCOR1_HUMAN antibody, REST corepressor 1 antibody, Retinoic acid receptor RXR-beta antibody, Retinoid X receptor beta antibody, Rxrb antibody

    UniProt
    Q9UKL0
    Pathways
    Regulation of Hormone Metabolic Process, Chromatin Binding
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