RPE65 Antikörper (AA 348-484) (HRP)

Produktnummer ABIN7167827

Produktdetails anti-RPE65 Antikörper (HRP)

Target: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Bindungsspezifität: AA 348-484

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPE65 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Retinoid isomerohydrolase protein (348-484AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RPE65

Target: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Andere Bezeichnung: RPE65 (RPE65 Produkte)

Hintergrund:

Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Aliases: All-trans-retinyl-palmitate hydrolase antibody, LCA 2 antibody, LCA2 antibody, Leber congenital amaurosis antibody, mRPE 65 antibody, mRPE65 antibody, p63 antibody, rd 12 antibody, rd12 antibody, Retinal pigment epithelium specific 61 kDa protein antibody, Retinal pigment epithelium specific 65 kDa protein antibody, Retinal pigment epithelium specific protein antibody, Retinal pigment epithelium specific protein 65 kDa antibody, Retinal pigment epithelium-specific 65 kDa protein antibody, Retinitis pigmentosa 20 antibody, Retinoid isomerohydrolase antibody, Retinol isomerase antibody, RP 20 antibody, RP20 antibody, RPE 65 antibody, RPE65 antibody, RPE65_HUMAN antibody, sRPE 65 antibody, sRPE65 antibody

UniProt: Q16518