RHOB Antikörper (AA 1-196) (Biotin)

Produktnummer ABIN7168019

Produktdetails anti-RHOB Antikörper (Biotin)

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Bindungsspezifität: AA 1-196

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOB Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RHOB

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Andere Bezeichnung: RHOB (RHOB Produkte)

Synonyme: ARH6 antikoerper, ARHB antikoerper, MST081 antikoerper, MSTP081 antikoerper, RHOH6 antikoerper, AA017882 antikoerper, Arh6 antikoerper, Arhb antikoerper, RHO antikoerper, arha antikoerper, rhoa antikoerper, wu:fj42e08 antikoerper, zgc:92206 antikoerper, rhob antikoerper, xrhob antikoerper, ras homolog family member B antikoerper, ras homolog gene family, member Ab antikoerper, ras homolog family member B S homeolog antikoerper, RHOB antikoerper, Rhob antikoerper, rhoab antikoerper, rhob.S antikoerper

Hintergrund:

Background: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Aliases: Aplysia RAS-related homolog 6 antibody, ARH6 antibody, ARHB antibody, H6 antibody, MST081 antibody, MSTP081 antibody, oncogene RHO H6 antibody, ras homolog family member B antibody, ras homolog gene family, member B antibody, Rho cDNA clone 6 antibody, Rho related GTP binding protein RhoB Precursor antibody, Rho-related GTP-binding protein RhoB antibody, Rhob antibody, RHOB_HUMAN antibody, RHOH6 antibody

UniProt: P62745