ROBO1 Antikörper (AA 29-143) (HRP)
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- Target Alle ROBO1 Antikörper anzeigen
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
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Bindungsspezifität
- AA 29-143
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ROBO1 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Roundabout homolog 1 protein (29-143AA)
- Isotyp
- IgG
- Top Product
- Discover our top product ROBO1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- Andere Bezeichnung
- ROBO1 (ROBO1 Produkte)
- Synonyme
- DUTT1 antikoerper, SAX3 antikoerper, AW494633 antikoerper, AW742721 antikoerper, Gm310 antikoerper, ROBO1 antikoerper, dutt1 antikoerper, roundabout antikoerper, sax3 antikoerper, MGC122264 antikoerper, roundabout-1 antikoerper, roundabout guidance receptor 1 antikoerper, roundabout, axon guidance receptor, homolog 1 (Drosophila) antikoerper, roundabout guidance receptor 1 L homeolog antikoerper, ROBO1 antikoerper, Robo1 antikoerper, robo1 antikoerper, robo1.L antikoerper
- Hintergrund
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Background: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its interaction with MYO9B, inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257). May be required for lung development (By similarity).
Aliases: Deleted in U twenty twenty antibody, DUTT 1 antibody, DUTT1 antibody, FLJ21882 antibody, H Robo 1 antibody, H-Robo-1 antibody, hRobo 1 antibody, Robo 1 antibody, Robo1 antibody, ROBO1_HUMAN antibody, Roundabout 1 antibody, Roundabout axon guidance receptor homolog 1 antibody, Roundabout homolog 1 antibody, Roundabout homolog1 precurser antibody, Roundabout1 antibody, SAX 3 antibody, SAX3 antibody
- UniProt
- Q9Y6N7
- Pathways
- Positive Regulation of Endopeptidase Activity
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