Rubicon Antikörper (AA 518-733)

Produktnummer ABIN7168473

Produktdetails anti-Rubicon Antikörper

Target: Rubicon (KIAA0226) (KIAA0226)

Bindungsspezifität: AA 518-733

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rubicon Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Rubicon

Target: Rubicon (KIAA0226) (KIAA0226)

Andere Bezeichnung: RUBCN (KIAA0226 Produkte)

Synonyme: RUBICON antikoerper, 5330403K09 antikoerper, Kiaa0226 antikoerper, Rubicon antikoerper, mKIAA0226 antikoerper, RUN and cysteine rich domain containing beclin 1 interacting protein antikoerper, KIAA0226 antikoerper, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antikoerper, RUBCN antikoerper, KIAA0226 antikoerper, Rubcn antikoerper

Hintergrund:

Background: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).

Aliases: Baron antibody, Beclin 1 associated RUN domain containing protein antibody, Beclin-1 associated RUN domain containing protein antibody, hypothetical protein LOC9711 antibody, Kiaa0226 antibody, OTTHUMP00000208021 antibody, OTTHUMP00000208023 antibody, OTTHUMP00000208024 antibody, RUBIC_HUMAN antibody, Rubicon antibody, RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody, Run domain Beclin 1 interacting and cystein rich containing protein antibody, Run domain Beclin-1 interacting and cysteine-rich containing protein antibody, RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody

UniProt: Q92622

Pathways: Autophagie